Human Sera
Cayman Chemical Amiprofos-methyl, Purity: ≥98%, CAS: 36001-88-4, 50 mg
An herbicide; reversibly decreases H. vulgare root and shoot length and inhibits in vitro paclitaxel-induced tubulin polymerization in a dose-dependent manner; completely inhibits tubulin polymerization in Hemanthus endosperm cells at a concentration of 0.1 μM; inhibits calcium accumulation in corn mitochondria (ID50 = 140 nM) and induces a 3-fold increase in the rate of calcium efflux from rat liver mitochondria at a concentration of 100 nM; inhibits the growth of P. falciparum (IC50 = 3.5 μM); completely inhibits microtubule polymerization in P. falciparum trophozoites at a concentration of 20 μM
Cayman Chemical Tenatoprazole, Purity: ≥98%, CAS: 113712-98-4, 50 mg
A proton pump inhibitor, blocking hog gastric H+/K+-ATPase activity with an IC50 value of 6.2 µM; blocks induced gastric acid secretion and ulcer formation in rats and humans
Cayman Chemical Trimetazidine (hydrochloride), Purity: ≥98%, CAS: 13171-25-0, 100 mg
An analytical reference standard categorized as a piperazine; has been detected as an AAF during anti-doping testing; intended for research and forensic applications
Cayman Chemical Levobunolol (hydrochloride), Purity: ≥98%, CAS: 27912-14-7, 50 mg
A β-adrenergic receptor antagonist that acts as a vasodilator and increases ocular circulation; formulations containing levobunolol are used to manage glaucoma
Cayman Chemical Betulonaldehyde, Purity: ≥95%, CAS: 4439-98-9, 100 mg
A pentacyclic triterpenoid; active against P. falciparum (IC50 = 3.36 µg/ml); cytotoxic to NCI H187 and Vero cells (IC50s = 19.23 and 17.09 µg/ml, respectively); reduces TPA-induced ear edema in mice at 1 mg/ear; has also been used a precursor in the semisynthesis of C-2 and C-28 betulonic aldehyde derivatives
Cayman Chemical N-Demethylvancomycin (hydrochloride), Purity: ≥95%, CAS: 198774-23-1, 50 mg
A glycopeptide antibiotic; active against several strains of S. aureus and S. epidermidis in vitro and in vivo
Cayman Chemical Trofosfamide, Purity: ≥95%, CAS: 22089-22-1, 50 mg
A nitrogen mustard alkylating agent and a derivative of cyclophosphamide with antiproliferative activities; increases the number of micronucleated polychromatic red blood cells isolated from mouse bone marrow at 40, 80, and 160 mg/kg; inhibits proliferation of isolated splenocytes in the allogenic mixed lymphocyte reaction at 100 mg/kg; reduces sheep red blood cell-induced increases in the number of antibody-producing spleen cells isolated from rats at 40 mg/kg
![Cayman Chemical 2-Amino-3-methylimidazo[4,5-f]quinoline, Purity: ≥98%, CAS: 76180-96-6, 50 mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502986648.png-250.jpg)
Cayman Chemical 2-Amino-3-methylimidazo[4,5-f]quinoline, Purity: ≥98%, CAS: 76180-96-6, 50 mg
A food-derived carcinogen; metabolized by CYP1A2 and conjugated by N-acetyltransferase or sulfotransferase to a metabolite that reacts with DNA to form adducts; induces formation of single-base substitutions and exon deletions and increases cell death in vitro; increases incidence of squamous cell hyperplasias in the stomach of p53 knockout mice; increases hepatocellular lesions in female mice regardless of p53 status
Cayman Chemical CID-2818500, Purity: ≥98%, CAS: 1215-07-2, 100 mg
An inhibitor of PRMT1 (IC50 = 11 μM in a histone H4 methylation assay); inhibits histone H4 methylation by PRMT8, but not histone H3.1 methylation by CARM1 or Set7/9, at 10 and 100 μM
Cayman Chemical Betamethasone Dipropionate, Purity: ≥98%, CAS: 5593-20-4, 100 mg
A synthetic corticosteroid and prodrug from of betamethasone; binds to the glucocorticoid receptor (IC50 = 5.25 nM); decreases the number of circulating eosinophils in dogs; reduces croton oil-induced exudate formation in a granuloma pouch assay in rats
Cayman Chemical Defensamide, Purity: ≥98%, CAS: 1104874-94-3, 100 mg
An SPHK1 activator; increases S1P levels in primary human keratinocytes but does not affect S1P lyase activity in the same cells at 100 µM; increases protein levels of LL-37 in primary human keratinocytes at 100 µM; inhibits invasion of S. aureus into murine skin ex vivo; has been used as an intermediate in the synthesis of sinuxylamide A as well as compounds with anticancer and antibacterial activities
Cayman Chemical NRG-3 (hydrochloride), Purity: ≥98%, CAS: 2701928-05-2, 50 mg
A substituted cathinone that is structurally analogous to pentylone, with the methylenedioxy group replaced with a naphthyl group
Cayman Chemical Curcumol, Purity: ≥95%, CAS: 4871-97-0, 100 mg
A sesquiterpene alcohol with diverse biological activities; a PAM of GABAA receptors that potentiates GABA-induced currents in hippocampal neurons; reduces activation of proinflammatory NF-κB and profibrotic TGF-β1/SMAD signaling pathways in RAW 264.7 cells stimulated with cigarette smoke extract from 1-200 μg/ml; inhibits proliferation of and induces apoptosis in LoVo and SW480 colorectal cancer cells; reduces tumor volume in a LoVo mouse xenograft model from 20-80 mg/kg; increases the rate of wound closure in rats with streptozotocin-induced diabetes
Cayman Chemical Pinacidil (hydrate), Purity: ≥95%, CAS: 85371-64-8, 100 mg
A potassium channel opener, activating the ATP-modulated potassium channels of guinea pig bladder and heart with Ki values of 104 and 251 nM, respectively; completely relaxes coronary artery rings preconstricted with serotonin (IC50 = 1.26 µM)
Cayman Chemical 4-methoxy-α-Pyrrolidinobutiophenone (hydrochloride), Purity: ≥98%, CAS: 2749897-35-4, 50 mg
A pyrovalerone analog that shares structural features with 4-MeO-α-PVP and 4-MePBP; intended only for forensic and research applications