Human Sera
Cayman Chemical FIdaxomycIn 100mg
A substituted benzylpiperazine with a potential for abuse intended for forensic and research applications
Cayman Chemical 5Deoxy5methylthIoadenosI 100mg
An entactogen belonging to the amphetamine and the phenethylamine classes that is structurally related to the MDA analog 5-APDB and MDMA intended for forensic and research purposes
Cayman Chemical ZalcItabIn 100mg
A potent agonist of GPR183 that induces specific activation of the receptor with an EC50 value of 50 nM (Kd 450 pM) acts as a potent chemokine affecting migration of immune cells expressing GPR183 both in vitro (EC50 500 pM) and in vivo
Cayman Chemical DarIfenacInhydrobromIde 100mg
An active metabolite of nitazoxanide active against M. tuberculosis (MIC 16 Ug/ml) reduces the growth of L. mexicana and T. cruzi in vitro (IC50s 6.2 and 17.5 M respectively) inhibits influenza A replication (EC50s 0.3-1 M) inhibits hepatitis B and hepatitis C virus replication (EC50 0.15 M for both)
Cayman Chemical MecamylamInhydrochlorIde 50mg
Immunogen Synthetic peptide from the C-terminal region of human NF-KB (p65) Host Mouse Species Reactivity ( ) Human mouse rat Applications ELISA MW 65 kDa
Cayman Chemical VatlnIbhydrochlorIde 50mg
A tyrphostin that is a poor inhibitor of EGFRK (IC50 450 M) and PDGFRK (IC50 100 M) which has been found to inhibit the phosphorylation of ERK1 and ERK2 at 25-50 M blocks the production of TNF-a attenuating signaling through NF-KB the induced expression of COX-2 and iNOS and the inflammatory response
Cayman Chemical 7-MethylgunosIn 50mg
An azapeptide inhibitor of HIV-1 protease (Ki 2.66 nM). It has antiviral activity against a variety of HIV-1 strains in several cell types (EC50 2.62-5.28 nM) exhibits a minor synergistic effect when used in combination with zidovudine in HIV-1-infected human PBMCs and an additive effect when used in combination with several additional reverse transcriptase or HIV-1 protease inhibitors inhibits UGT1A1 which is involved in bilirubin clearance
Cayman Chemical R S-AMPAhydrate 50mg
A sterol glycoside with diverse biological activities active against E. coli and S. aureus inhibits a-amylase and a-glucosidase and scavenges DPPH radicals (IC50s 46.4 17 and 155 UM respectively) inhibits the proliferation of HepG2 and SMMC-7721 hepatocellular carcinoma cells (IC50s 143.4 and 138.73 Ug/ml respectively) and migration and invasion in the same cells at 50 or 100 Ug/ml increases survival and decreases the number of kidney CFUs in a mouse model of candidiasis induced by C. albicans
Cayman Chemical BromocrIptInmesylate 50mg
An agonist of PPARY (EC50 0.05 UM) selective for PPARY over PPARa and PPAR in transactivation assays (EC50s 3.99 and 10 UM respectively)
Cayman Chemical Cordyceps mIlItarIs 50mg
Source Human blood all source material tested and found non-reactive to HTLV-III and HBsAg using FDA approved assay methods Mr 38 kDa
Cayman Chemical IvabradInhydrochlorIde 100mg
1314-dihydro PGE1 is a biologically active metabolite of PGE1 with comparable potency to the parent compound.{4168182} It is an inhibitor of ADP-induced platelet aggregation in human PRP and washed platelets with IC50 values of 31 and 21 nM respectively.{1607} 1314-dihydro PGE1 is a slightly more potent inhibitor of ADP-induced human platelet aggregation than PGE1 which has an IC50 of 40 nM.{960} Also 1314-dihydro PGE1 was shown to activate adenylate cyclase in NCB-20 hybrid cells with a Kact of 668 nM.{1926}
Cayman Chemical ChlorthalIdon 50mg
An analytical reference standard categorized as a tryptamine induces the HTR in mice substitutes for DOM in a two-lever drug discrimination test in rats intended for research and forensic applications
Cayman Chemical CntharIdIn 100mg
An analytical reference standard aBcarboline alkaloid and MAO inhibitor has been found as an additive in herbal mixtures containing synthetic cannabinoids has been described as contributing to poisoning when combined with tryptamines a minor component of ayahuasca intended for research and forensic applications